XEOMIN®
Some neuromodulators do the job, but XEOMIN® does it better. As the only double-filtered neurotoxin on the market, XEOMIN® is formulated without the accessory proteins found in other injectables, which means cleaner results and a treatment that holds up over time. At Serenity Aesthetics & Wellness, our injectors use it to smooth frown lines, forehead lines, and crow’s feet with precision that looks natural and lasts.
XEOMIN®
Some neuromodulators do the job, but XEOMIN® does it better. As the only double-filtered neurotoxin on the market, XEOMIN® is formulated without the accessory proteins found in other injectables, which means cleaner results and a treatment that holds up over time. At Serenity Aesthetics & Wellness, our injectors use it to smooth frown lines, forehead lines, and crow’s feet with precision that looks natural and lasts.
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What 
Is XEOMIN®?
XEOMIN® (incobotulinumtoxinA) is a prescription injectable treatment used to smooth away those stubborn lines that form on our forehead and around our eyes. While it works similarly to other popular wrinkle relaxers, it has one major advantage: it is pure.
Through a special process called XTRACT Technology™, XEOMIN® is double-filtered to remove complexing proteins. Most other treatments leave these proteins in the formula, which can eventually cause your body to build up resistance, making the treatments less effective over time. Because XEOMIN® is purified to only the essential ingredients, your body is less likely to develop those antibodies, helping you get consistent results every time you visit.
This FDA-approved injectable is a great choice for softening horizontal forehead lines, vertical “11s” between the brows, and delicate crow’s feet around the eyes. Most patients begin to see a refreshed appearance within just 2 weeks, with results that typically last about 3-4 months. By choosing a purified formula, you’re not just treating today’s wrinkles, you’re choosing a smart, simple approach to long-term maintenance.
How Does XEOMIN® Work?
XEOMIN® works by temporarily interrupting the signal between the nerve and the muscle at the injection site. The upper facial lines that concern most patients are called dynamic wrinkles, meaning they form as a direct result of repeated muscle contractions from expressions like frowning, squinting, and smiling. By relaxing those muscles beneath the skin’s surface, XEOMIN® smooths the overlying skin without freezing your face or flattening your expressions.
What makes XEOMIN® stand out from other neuromodulators is its double-filtered manufacturing process. Using XTRACT Technology™, Merz removes the complexing proteins found in competing products, leaving only what is needed for the treatment to work. This leaner formula means the body has less reason to mount an immune response against it, making XEOMIN® a reliable option for patients committed to maintaining their results over time.
Treatment is fast, typically 10-15 minutes, with results beginning to appear within 2 weeks and lasting approximately 3-4 months.
What Are The Benefits Of XEOMIN®?
XEOMIN® delivers proven, consistent results with a purity-first formula that stands apart from every other neuromodulator on the market.
At Serenity Aesthetics & Wellness, every XEOMIN® treatment is tailored to your individual facial anatomy by providers with over a decade of injection expertise.
The Treatment Process
Your XEOMIN® journey at Serenity begins with a one-on-one consultation with one of our experienced injectors. Your provider will assess your facial anatomy, review your aesthetic goals, and evaluate which areas to address. This is also the time to share your medical history, current medications, and any prior experience with neuromodulators. A thorough consultation ensures your treatment plan is built around your specific face and goals, not a generic protocol.
During your appointment, your provider will observe your facial expressions in real time to determine precise injection placement, then administer XEOMIN® using a fine needle into the targeted muscles. The recommended starting doses are 20 units for frown lines, 20 units for forehead lines, and 24 units total for crow’s feet, though your provider will personalize your dose based on your anatomy and desired results. The full treatment typically takes 10-15 minutes.
XEOMIN® requires minimal downtime. For the 24 hours following treatment, avoid strenuous exercise, refrain from rubbing or massaging the treated areas, skip alcohol to reduce the risk of bruising, and stay upright for the first few hours post-injection. Most patients return to their routine the same day.
Results begin to show within 2 weeks, with most patients reaching full improvement by the end of the first month. The smoothing effects last approximately 3-4 months, at which point your Serenity provider can schedule a follow-up to keep your results looking their best.
Common FAQs
Is XEOMIN® The Same As BOTOX®?
While both are wrinkle relaxers made with the same active ingredient, the main difference is that XEOMIN® undergoes an additional purification step to remove unnecessary proteins. Other brands leave these complexing proteins in the mix, which can occasionally cause your body to build a tolerance, making treatments feel less effective over time.
Can I Combine XEOMIN® With Other Treatments?
Yes, and many patients do. One of Serenity's core strengths is our ability to build personalized, multi-modal treatment plans. XEOMIN® works well with dermal fillers, biostimulators, and skin resurfacing treatments to address volume loss, texture, and tone alongside dynamic wrinkles.
What Should I Avoid After My XEOMIN® Treatment?
For the first 24 hours after treatment, avoid strenuous physical activity, alcohol consumption, and rubbing or massaging the treated areas. You should also remain upright for the first few hours following your appointment to reduce the risk of the neuromodulator spreading from the target areas.
Will I Still Be Able To Make Facial Expressions?
Absolutely. By precisely targeting only the specific muscles responsible for deep wrinkles, you’ll still be able to smile, frown, and look surprised, but without the heavy skin creasing that often accompanies those movements.
How Many Units Will I Need?
Each face requires a different number of units. During your consultation, we’ll examine how your face moves to determine the right amount to give you a refreshed look while still maintaining your natural expressions. Our goal is always to use the precise amount needed to get the results you want without ever looking overdone.
Start Your Transformation
Choosing XEOMIN® at Serenity Aesthetics & Wellness in San Francisco and Burlingame, California, means choosing a purified, high-performance treatment that respects your body’s natural chemistry while delivering the smooth, refreshed look you’re after. Whether you’re maintaining your glow or starting your aesthetic journey, our expert injectors are here to ensure your results look as natural as you feel. Book your consultation today and experience the beauty of a simpler, cleaner formula.
